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| Rachel McAdams | Clare Abshire |
| Eric Bana | Henry DeTamble |
| Ron Livingston | Gomez |
| Arliss Howard | Richard DeTamble |
| Stephen Tobolowsky | Dr. David Kendrick |
| Alex Ferris | Young Henry |
| Brooklynn Proulx | Young Clare |
| Michelle Nolden | Annette DeTamble |
| Jane McLean | Charisse |
| Tatum McCann | Young Alba |
| Katherine Trowell | Hospital Receptionist |
| Bart Bedford | Library Researcher |
| Esther Jun | Waitress |
| Matt Birman | Chicago Police #1 |
| Craig Snoyer | Chicago Police #2 |
| Carly Street | Librarian |
| Romyen Tangsubutra | Thai Waiter |
| Director | Robert Schwentke
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| Producer | Brad Grey
Nick Wechsler Richard Brener |
| Writer | Bruce Joel Rubin
Audrey Niffenegger |
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Henry DeTamble (Eric Bana) is a Chicago librarian with an odd problem: he has a genetic disorder that sends him hurtling through time when he is under distress. In spite of this challenge, Henry tries to build a stable life with the woman he loves, Clare (Rachel McAdams). Though they are married, Henry disappears and reappears randomly throughout Clare's life. With the challenges of a regular relationship coupled on top of this difficult challenge, the two try to find a way to have a happy life together. |
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